News Video | Policy | GPs | Hospitals | Medical | Mental Health | Welfare | Search


Prescribing Information For Depo-Provera

19th November

Pfizer New Zealand Statement Regarding Additional Prescribing Information For Depo-Provera

Pfizer New Zealand has submitted information to Medsafe regarding the potential for bone mineral density changes in women and adolescents taking DEPO PROVERA, a long acting injectable contraceptive, and is awaiting their decision regarding additional warning statements, Pfizer New Zealand General Manager Mark Crotty said today.

Pfizer Inc released the following statement yesterday concerning additional prescribing information for DEPO-PROVERA:

“Pfizer has worked closely with the U.S Food and Drug Administration and has begun alerting healthcare professionals and patients about revised labelling for DEPO-PROVERA regarding the potential for bone mineral density changes in women and adolescents.”

“The primary change in the US Prescribing Information is the addition of more prominent wording in a boxed warning noting that women who use DEPO–PROVERA may lose significant bone density. The revised food labelling further notes that bone loss is greater with increasing duration of use and may not be completely reversible and that DEPO–PROVERA should be used as a long-term birth control method (e.g. longer than 2 years) only if other birth control methods are inadequate.”

Following Medsafe’s decision Pfizer NZ will be writing to all healthcare professionals concerned.

The current New Zealand prescribing information already contains a warning that use of the product may be considered among the risk factors for the development of osteoporosis. Additional clinical research was initiated to clarify the effects of DEPO–PROVERA on bone mineral density in women aged 25-35 and adolescents. The results of theses studies were recently submitted to the FDA and are reflected in the revised labelling for DEPO–PROVERA in the US.

Pfizer Inc has noted that its studies indicated that a decrease in bone mineral density appears to be at least partially reversible in both adults and adolescents when the use of DEPO–PROVERA is discontinued. A study to assess the reversibility of loss of bone mineral density in adolescents is ongoing.


© Scoop Media

Culture Headlines | Health Headlines | Education Headlines


Electronica: Restoring The World’s First Recorded Computer Music

University of Canterbury Distinguished Professor Jack Copeland and UC alumni and composer Jason Long have restored the earliest known recording of computer-generated music, created more than 65 years ago using programming techniques devised by Alan Turing. More>>


Scoop Review Of Books: Almost Getting Away With Murder

The Black Widow by Lee-Anne Cartier: Lee-Anne Cartier is the sister of the Christchurch man found to have been murdered by his wife, Helen Milner, after an initial assumption by police that his death, in 2009, was suicide. More>>

Howard Davis: Triple Echo - The Malevich/Reinhardt/Hotere Nexus

Howard Davis: The current juxtaposition of works by Ralph Hotere and Ad Reinhardt at Te Papa perfectly exemplifies Jean Michel Massing's preoccupation with the transmigration of imagery in a remarkable triple echo effect... More>>

Scoop Review Of Books: Nō Tāu Manawa

Vaughan Rapatahana responds to Fale Aitu | Spirit House by Tusiata Avi: "fa’afetai Tusiata, fa’afetai, / you’ve swerved & served us a masterclass corpus / through graft / of tears & fears..." More>>

9 Golds - 21 Medals: NZ Team Celebrates As Rio 2016 Paralympic Games Close

The entire New Zealand Paralympic Team, led by kiwi sprinter and double gold medallist Liam Malone as flag bearer, are on the bus to the Maracanã Stadium in Rio de Janeiro for the Closing Ceremony of the Rio 2016 Paralympic Games. There, they will celebrate the fantastic successes of the past 10 days. More>>


New Zealand Improv Festival: The Festival Of Moments To Return To The Capital

The eighth incarnation of the New Zealand Improv Festival comes to BATS Theatre this 4-8 October , with a stellar line-up of spontaneous theatre and instant comedy performed and directed by top improvisors from around New Zealand and the world. More>>


Get More From Scoop



Search Scoop  
Powered by Vodafone
NZ independent news