News Video | Policy | GPs | Hospitals | Medical | Mental Health | Welfare | Search

 


Predicting breast cancer recurrence

ROYAL AUSTRALASIAN COLLEGE OF SURGEONS MEDIA RELEASE


Predicting breast cancer recurrence

Wednesday 8 May, 2013

While several factors can help predict breast cancer recurrence, less is known about the influence these factors have on the pattern of recurrence, notably its timing and site, delegates to the 82nd Annual Scientific Congress (ASC) of the Royal Australasian College of Surgeons have been told.

Danielle Fitzpatrick, a medical student at the University of Adelaide, told an audience of specialist breast surgeons that recurrence could be predicted by tumour size, grade, oestrogen receptor (ER) status and the degree of lymph node (LN) involvement.

“Our study aimed to identify patient and tumour characteristics that predict risk periods for breast cancer relapse,” Miss Fitzpatrick said.

“We studied a cohort of 473 patients who presented to The Queen Elizabeth Hospital with recurrent breast cancer between 1968 and 2008. Patient and primary tumour characteristics were collected, including age, menopausal status, tumour grade, size (<2 or =2 cm), ER and progesterone receptor (PR) status and LN involvement. These factors were modelled against time to breast cancer relapse using Kaplan-Meier survival curves.

“”High tumour grade, size =2cm, ER negativity and PR negativity were all shown to significantly correlate with a higher incidence of earlier recurrence. Patients with ER negative disease who relapsed were almost twice as likely to present within two years of diagnosis than those with ER positive disease.

“Interestingly, LN involvement did not significantly correlate with time to relapse, but was shown to predict site of recurrence. Distant recurrences were found to be higher in node positive patients who relapsed (62%) compared with node negative patients (38%).

“Using these predictors will enable more tailored surveillance strategies with more appropriate discharge to primary care,” Miss Fitzpatrick said.

Approximately 1200 surgeons from New Zealand, Australia and around the world are attending the ASC, which runs from 6 to 10 May and is being held at Auckland’s Skycity/Crowne Plaza Convention Centre.

ENDS


© Scoop Media

 
 
 
 
 
Culture Headlines | Health Headlines | Education Headlines

 

Scoop Review Of Books: Rushing For Gold

The first section focuses particularly on the Victorian connections – commercial, legal, mining and personal, including migration statistics. But for me the most interesting chapters were in the middle sections about the people of the goldfields. More>>

Comedy Festival Review: VOTE BATT

The political campaigning in the US over the last eight months or so has provided a stark insight into how far political candidates are willing to go. This background came into focus as “former comedian” – now politician – Tim Batt ushered people up into the front seats, passing out badges and taking photographs with his not entirely adoring public... More>>

HRH QEII's 90th: New Zealand Post Birthday Stamps Fit For A Queen

New Zealand Post is celebrating the Queen’s 90th birthday with a special series of stamps and a limited edition silver coin. The Queen was born on 21 April 1926. To mark her birthday, New Zealand Post has produced ‘lenticular’ or moving stamps that feature nine different images of the Queen on just three stamps. More>>

ALSO:

Anzac Day: A Time To Stand Against Hatred

The Human Rights Commission says ANZAC Day is a time for New Zealanders to remember those things our grandparents stood for and stand up against intolerance and prejudice. More>>

ALSO:

Get More From Scoop

 
 

LATEST HEADLINES

 
 
 
 
Health
Search Scoop  
 
 
Powered by Vodafone
NZ independent news