Top Scoops

Book Reviews | Gordon Campbell | Scoop News | Wellington Scoop | Community Scoop | Search


Research Shows Old Stem Cells Can Turn Cancerous

Scoop Report: Research Shows Old Stem Cells Can Turn Cancerous

By Marietta Gross - Scoop Media Auckland.

Stem cells from human adipose tissue have turned cancerous in a study with laboratory animals. The malignant tumours were formed through cells which had been cultivated outside of the body.

The researchers had expected that such adult stem cells normally wouldn’t form malignant tumours, which is a familiar problem within embryonic stem cells.

A risk for humans, who have already been treated with stem cells from their bone marrow, would not exist, say the researchers. Cells which are applied in such a therapy are cultivated only in a short time outside the body.

“Under normal circumstances of a clinical application we regard these cells as fairly safe”, said Antonio Bernad from the Autonomous University of Madrid, who led the research. “But we should be cautious.”

The scientists see a connection between the number of divisions of the cells outside the body and the risk for cancer. The team examined the so called mesenchymal stem cells, which were divided in the laboratory 90 to 140 times, before they were injected into the subjects.

Only one in 10,000 cells in the bone marrow is a mesenchymal one. They can develop into different tissue types such as bone cells, muscle cells and neurons.

The older cells are more vulnerable to generate cancer. Bernad is convinced that the key was not to let these cell cultures grow too long. The researchers warned, that only little amounts of stem cells should be proliferated over many generations and demand a general growth limitation of about 60 generations for these cell cultures.


© Scoop Media

Top Scoops Headlines


Jan Rivers: The New Zealanders Involved In Brexit

There are a number who have strong connections to New Zealand making significant running on either side of the contested and divisive decision to leave the European Union. More>>

Rawiri Taonui: The Rise, Fall And Future Of The Independent Māori Parties

Earlier this month the Māori Party and Mana Movement reflected on the shock loss of their last parliamentary seat in this year’s election. It is timely to consider their future. More>>

Don Rennie: Is It Time To Take ACC Back To First Principles?

The word “investing” has played a major part in the operations of the ACC since 1998... More>>

Using Scoop Professionally? Introducing ScoopPro

ScoopPro is a new offering aimed at ensuring professional users get the most out of Scoop and support us to continue improving it so that Scoop continues to exist as a public service for all New Zealanders. More>>