Book Reviews | Gordon Campbell | News Flashes | Scoop Features | Scoop Video | Strange & Bizarre | Search

 


Asthma drug Singulair linked to suicidality

Asthma drug Singulair linked to suicidality

by Martha Rosenberg
May 6, 2013

World sales of Merck's blockbuster asthma drug, Singulair, were about $5 billion a year until last year when its patent expired in the United States. But the drug also has a darkening cloud over it. The Australian medicine watchdog has received 58 reports of adverse psychiatric events in children and teenagers taking Singulair since 2000 and reports have also surfaced in the US.

Singulair, a leukotriene receptor antagonist or LTRA, is one of several "add-on" asthma drugs that were debuted in the last decade. Patients are supposed to add the new, "asthma controller" drugs to their regular rescue inhalers and inhaled corticosteroids not replace them. Ka-ching.

In the US, Singulair was heavily marketed for minor childhood allergies, in addition to asthma, and sold in a cherry-flavored chewable formulation. Merck had marketing partnerships with Scholastic, a leading educational publishing group, and the American Academy of Pediatrics, reported the US' Fox News.

Sales pieces from the Scholastic/ Merck partnership cajoled parents, "When your child breathes in an asthma trigger, such as pollen from trees or weeds, the body releases leukotrienes (loo-ko-TRY-eens)" which Singulair blocks. But they also told parents their children could experience, "hallucinations (seeing things that are not there), irritability, restlessness, sleepwalking, suicidal thoughts and actions (including suicide), trembling, and trouble sleeping," on the drug. At least they wouldn't be sniffling.

In 2009, after 15-year-old Cody Miller of Queensbury, NY was given Singulair for hay fever and took his own life 17 days later, the US Food and Drug Administration (FDA) gave Singulair a stronger warning for "neuropsychiatric" side effects. The next year, Fox TV, a leading US television network, reported that children on Singulair are being diagnosed with ADHD, Tourette Syndrome and serious behavioral and neurological conditions caused by the drugs. Most are "cured" when they go off the drug but some are not and are then given other damaging pediatric behavioral drugs.

Over 100 parents on the popular US drug-rating web site askapatient.com, corroborate the evidence, reporting that Singulair caused hyperactivity, tantrums, depression, crying, school trouble, facial tics, strange eye movements and self-harm in their children, some as young as one year old. Many of the children were prescribed Singulair for sniffles and wheezing which were called early symptoms of asthma, commensurate with Pharma's "early treatment" business model.

"Last night was a complete meltdown over every single thing that could have possibly been a minor annoyance, such as not being able to squeeze enough toothpaste out of the tube, which culminated in a 30-minute screaming and crying bonanza," writes the mother of a 7-year-old who has been on Singulair for six months. "I was reading stories to her tonight, and she must have popped her jaw open at least 40 times over the course of two
books (mouth open wide like a yawn in fast-forward). I was keeping an eye on her, and a few times I asked her why she kept doing that and she said she didn't know, and she thought maybe her mouth was 'itchy.'"

"Do NOT recommend this drug to other parents," writes another mother. "4 year olds that suddenly talk about killing themselves are influenced by a DRUG!!"

Even adults are put on Singulair for minor reasons with major consequences. "I was perfectly healthy prior to taking this drug," reports a 53-year-old woman about Singulair on the askapatient web site. "Doc noticed I had a little wheeze and prescribed Singulair. I began to have the dreams, insomnia and depression after the first few days," which led to "suicidal thoughts," she says.

Like many of Big Pharma's blockbuster drugs, Singulair made billions by selling "diseases"--in this case childhood allergies and asthma. And like many blockbuster drugs, the true dangers have only emerged since the drug went off patent and the profit potential was gone.

*************

Read more about underreported prescription drug dangers in Martha Rosenberg's acclaimed expose, Born with a Junk Food Deficiency, available in bookstores, libraries, and online.

© Scoop Media

 
 
 
 
 
Top Scoops Headlines

 

Until Dawn: Pick Your Own Horrible Adventure

Suppermassive Games’ Until Dawn sees a group of dumb sexy teenagers take a trip to a spooky mansion atop a mountain. It is, obviously, a horror game. However, the game is so ridiculous it turns out to be more of a comedy. Until Dawn begins with ... More>>

Gordon Campbell: On Donald Trump, And Dr Dre

For the past few months, you, me, and Rupert Murdoch have been waiting for the wheels to fall off the Trump campaign, and for some drab incarnation of business-as-usual (Jeb Bush, Scott Walker) to emerge as the real Republican standard bearer in next year’s presidential election... More>>

ALSO:

Hiroshima: 70 Years On, The Nuclear Threat Looms As Large As Ever

Rumours had been circulating in Hiroshima that the city was being saved for something special. It was. The burst of ionising radiation, blast, heat and subsequent firestorm that engulfed the city on August 6 killed 140,000 people by the end of 1945. More>>

ALSO:

#FutureOfNews: Challenge & Solution - A ''New Scoop''

The development of Scoop's new "Ethical Paywall" approach to licensing commercial use of its news content and addressing the current State of the NZ News Media and the challenges being faced news media everywhere. More>>

ALSO:

Lyndon Hood: God Defend The National Anthem

Recently Labour leader Andrew Little said – deliberately, I think – that he didn't like New Zealand's national anthem and many New Zealanders preferred to sing along to the Australian one. More>>

Keith Rankin: Centenary Of The Battle For Chunuk Bair

I don't agree with the view that our national identity was forged at Gallipoli, despite the rah-rah about this in the week leading up to Anzac Day... What concerns me now, however, is our lack of respect for our own history. Why have we switched off? More>>

ALSO:

Werewolf: Pitch Perfect

Among his other blessings, Pope Francis has been a gift to the world of marketing studies. There can be few other examples where a leader has transformed the perception of an enterprise so thoroughly, but without making any discernible change to its core principles. More>>

ALSO:

US Politics: The Democrats Try To Engage With America (Again)

Venues are being rebooked to accommodate the thousands of people coming to listen to Vermont Senator, avowed socialist, and presidential aspirant Bernie Sanders talk about the redistribution of wealth. More>>

ALSO:

Get More From Scoop

 
 
 
 
 
 
 
Top Scoops
Search Scoop  
 
 
Powered by Vodafone
NZ independent news