Gordon Campbell | Parliament TV | Parliament Today | News Video | Crime | Employers | Housing | Immigration | Legal | Local Govt. | Maori | Welfare | Unions | Youth | Search

 

Animal Research Failing – So Do More Animal Research?

Animal Research Failing – So Do More Animal Research?


Victoria University of Wellington is about to host a lecture on why the success rates of pharmaceutical development is so low and what can be done about it. The New Zealand Anti-Vivisection Society (NZAVS) welcomes discussion on this important issue and hopes that the lecture will signal a move towards better pharmaceutical development.

For decades drug development has relied almost exclusively on animal research which is based on the assumption that what is good for a rat is good for a human. Reliance on this has given success rates for drugs developed using animal models being below 10% when they reach the human trial stage. The NZ Anti-Vivisection Society say that it is time that researchers developed drugs using methods that give data relevant to humans.

“There is something fundamentally wrong with the methods being used when the success rates are that low. In any other industry if over 90% of new products developed end up being not fit for use the way they’re being developed would be scrapped. It is concerning when researchers are reported as calling for more of the same. We need fundamental changes to bring early drug development work into the 21st century, not calls for more of what doesn’t work.” said NZAVS spokesperson Stephen Manson.

“Researchers using animal models have been describing what they do as a ‘necessary evil’ for decades. It’s not a necessary, it’s dangerous. If something is clearly not working and is costing a business millions of dollars you don’t do more of it, you stop and find a better way. You don’t carry on using a failed model until something that works comes along; you work on finding something that leads to successes.

“Over 90% of the treatments that work in animal models don’t work in humans. This begs the question of how many treatments that didn’t work in rats would have worked in humans but were shelved at that stage. With that high a rate of false positives from rats there’s bound to be false negatives too. There may well be many potential treatments being ignored as researchers couldn’t make them work in whatever animal model they used.”

ends

© Scoop Media

 
 
 
Parliament Headlines | Politics Headlines | Regional Headlines

Spying On Politicians, Activists, Iwi, Quake Victims: "Failings Across Public Service"

A State Services Commission investigation into the use of external security consultants by government agencies has uncovered failings across the public service, including breaches of the code of conduct...

However, the inquiry found no evidence of widespread inappropriate surveillance by external security consultants on behalf of government agencies. More>>

 

Dope News: Binding Cannabis Referendum To Be Held At 2020 Election

The referendum on cannabis for personal use is part of Labour's confidence and supply agreement with the Greens. It could be one of potentially three referenda - decisions have yet to be made about euthanasia and changes to electoral laws. More>>

ALSO:

Vic: Victoria University Name Change Rejected

Education Minister Chris Hipkins has declined Victoria University of Wellington Council’s application for a legal name change. More>>

ALSO:

PM's Post-Cab 17/12/18: Chief Justice, M Bovis

Prime Minister Jacinda Ardern's final post-cabinet press conference of the year focussed on announcing the appointment of Helen Winkelmann as the next Chief Justice, and an update on effort to eradicate Mycoplasma bovis from New Zealand. More>>

ALSO:

Law Commission Issues Paper: Use Of DNA In Criminal Investigations

In the 22 years since the Act came into force, it has become clear that the modern-day fingerprint analogy is increasingly inapt... Theoretically, whole genome sequencing could ultimately become the standard method of analysing a DNA sample. Such a development will give a new perspective on the concept of genetic surveillance in the criminal context. More>>

State Highways: $1.4 Billion For Road Safety Improvements

The Safe Network Programme will make 870 kilometres of high volume, high-risk State Highways safer by 2021 with improvements like median and side barriers, rumble strips, and shoulder widening. More>>

ALSO:

Dealing Crackdown, Addiction Support: Government Action On Synthetics

The NZ Drug Foundation has welcomed the Government’s response to synthetic drug deaths. The response strikes a balance between giving law enforcement the tools they need to target criminal networks and changing drug law to make it easier for people to access help when they need it. More>>

ALSO:

Strategy Committee Unanimous: Wellington To Forge Ahead With Convention Centre

The three-storey Cable Street building, with around 18,000-square metres of floor space, will comfortably be able to host 1500 people for conventions. It includes a 1651sq m exhibition area that will attract international exhibitions too big for nearby Te Papa and provide an always-changing visitor attraction. More>>

ALSO:

 
 
 
 
 

LATEST HEADLINES

  • PARLIAMENT
  • POLITICS
  • REGIONAL
 
 

InfoPages News Channels