Gordon Campbell | Parliament TV | Parliament Today | News Video | Crime | Employers | Housing | Immigration | Legal | Local Govt. | Maori | Welfare | Unions | Youth | Search

 


Animal Research Failing – So Do More Animal Research?

Animal Research Failing – So Do More Animal Research?


Victoria University of Wellington is about to host a lecture on why the success rates of pharmaceutical development is so low and what can be done about it. The New Zealand Anti-Vivisection Society (NZAVS) welcomes discussion on this important issue and hopes that the lecture will signal a move towards better pharmaceutical development.

For decades drug development has relied almost exclusively on animal research which is based on the assumption that what is good for a rat is good for a human. Reliance on this has given success rates for drugs developed using animal models being below 10% when they reach the human trial stage. The NZ Anti-Vivisection Society say that it is time that researchers developed drugs using methods that give data relevant to humans.

“There is something fundamentally wrong with the methods being used when the success rates are that low. In any other industry if over 90% of new products developed end up being not fit for use the way they’re being developed would be scrapped. It is concerning when researchers are reported as calling for more of the same. We need fundamental changes to bring early drug development work into the 21st century, not calls for more of what doesn’t work.” said NZAVS spokesperson Stephen Manson.

“Researchers using animal models have been describing what they do as a ‘necessary evil’ for decades. It’s not a necessary, it’s dangerous. If something is clearly not working and is costing a business millions of dollars you don’t do more of it, you stop and find a better way. You don’t carry on using a failed model until something that works comes along; you work on finding something that leads to successes.

“Over 90% of the treatments that work in animal models don’t work in humans. This begs the question of how many treatments that didn’t work in rats would have worked in humans but were shelved at that stage. With that high a rate of false positives from rats there’s bound to be false negatives too. There may well be many potential treatments being ignored as researchers couldn’t make them work in whatever animal model they used.”

ends

© Scoop Media

 
 
 
 
 
Parliament Headlines | Politics Headlines | Regional Headlines

Gordon Campbell:
On The Kim Regime

During the Cuban Missile Crisis, the US had a very clear objective and eventually offered a quid pro quo of the removal of some of its own missiles from Turkey. This time, there’s no clarity about what the US is seeking, or offering.

It hasn’t helped that the US and the global media consistently agree on calling North Korea and its leadership “crazy” and “irrational” and urging it to “come to its senses”. When you treat your opponent as being beyond reason, it gets hard to comprehend what their strategy is, let alone work out the terms of a viable compromise. More>>

 

Recovery: Economic Impact Of Kaikōura Quake Revealed

The report details the impact on small businesses and tourism caused by disruptions to transport infrastructure and the economic impacts... The impact on New Zealand’s Gross Domestic Product (GDP) over the first 18 months following the earthquake has been estimated at $450-$500 million. More>>

ALSO:

Human Rights Commission: Urgent Need For Action On Seclusion And Restraint

Chief Human Rights Commissioner David Rutherford says that while the report makes for sobering reading, the focus should now be on how the recommendations can be used to reduce the occurrence of seclusion and restraint in New Zealand and, in circumstances where it is necessary, to improve practices. More>>

ALSO:

CORRECTIONS (March 2017):

SCHOOL SECLUSION ROOMS (2016):

$11bn Capital Spend, New Debt Target: Steven Joyce On Budget Priorities

First, delivering better public services for a growing country – providing all New Zealanders with the opportunity to lead successful independent lives... And finally, we remain committed to reducing the tax burden and in particular the impact of marginal tax rates on lower and middle income earners, when we have the room to do so. More>>

ALSO:

JustSpeak Report: Bail Changes To Blame For New Billion Dollar Prison

In 2013 criminal justice spending was falling and the Government was mulling over what to spend the money on. 3 years later there are 10,000 people in prison and a new billion dollar prison is announced. More>>

ALSO:

Get More From Scoop

 

LATEST HEADLINES

 
 
 
 
 
 
 
 
Politics
Search Scoop  
 
 
Powered by Vodafone
NZ independent news