Gordon Campbell | Parliament TV | Parliament Today | News Video | Crime | Employers | Housing | Immigration | Legal | Local Govt. | Maori | Welfare | Unions | Youth | Search

 

Animal Research Failing – So Do More Animal Research?

Animal Research Failing – So Do More Animal Research?


Victoria University of Wellington is about to host a lecture on why the success rates of pharmaceutical development is so low and what can be done about it. The New Zealand Anti-Vivisection Society (NZAVS) welcomes discussion on this important issue and hopes that the lecture will signal a move towards better pharmaceutical development.

For decades drug development has relied almost exclusively on animal research which is based on the assumption that what is good for a rat is good for a human. Reliance on this has given success rates for drugs developed using animal models being below 10% when they reach the human trial stage. The NZ Anti-Vivisection Society say that it is time that researchers developed drugs using methods that give data relevant to humans.

“There is something fundamentally wrong with the methods being used when the success rates are that low. In any other industry if over 90% of new products developed end up being not fit for use the way they’re being developed would be scrapped. It is concerning when researchers are reported as calling for more of the same. We need fundamental changes to bring early drug development work into the 21st century, not calls for more of what doesn’t work.” said NZAVS spokesperson Stephen Manson.

“Researchers using animal models have been describing what they do as a ‘necessary evil’ for decades. It’s not a necessary, it’s dangerous. If something is clearly not working and is costing a business millions of dollars you don’t do more of it, you stop and find a better way. You don’t carry on using a failed model until something that works comes along; you work on finding something that leads to successes.

“Over 90% of the treatments that work in animal models don’t work in humans. This begs the question of how many treatments that didn’t work in rats would have worked in humans but were shelved at that stage. With that high a rate of false positives from rats there’s bound to be false negatives too. There may well be many potential treatments being ignored as researchers couldn’t make them work in whatever animal model they used.”

ends

© Scoop Media

 
 
 
 
 
Parliament Headlines | Politics Headlines | Regional Headlines

Not Easy: Gordon Campbell On The Greens’ Ongoing Problems

Hard to treat the Greens’ belated decision to stand a candidate in Ohariu as being anything other than a desperation move, by a party whose own leadership is evidently concerned about its chances of survival...

A few months ago, the Greens felt able to forego that role in Ohariu in order to help a beleaguered Labour Party get its candidate Greg O’Connor across the line, and knock Peter Dunne out of the parliamentary frame. More>>

 

Closing The Gap: Ardern Rules Out Income Tax Rise

After earlier commitments by Jacinda Ardern to do something about inequality and poverty, this new position on income tax seems an about face. To do something significant about inequality requires increases in income for those at the bottom and decreases for those at the top... More>>

ALSO:

Gordon Campbell: On DHB Deficits And Free Trade

Currently the world is looking on aghast at the Trump administration’s plans to slash Obamacare, mainly in order to finance massive tax changes that will deliver most of their gains to the wealthy. Lives will be lost in the trade-off. Millions of Americans stand to lose access to the healthcare they need... More>>

Greens' Response: Slum-Like Rentals Exposed In Renting Review

“...The grim findings of the review are a wakeup call about the true state of rentals in this country. Too many renters are festering in slum-like conditions under the thumb of landlords who have largely unchecked powers and ignore tenants’ complaints when it suits them.” More>>

ALSO:

Gordon Campbell: On The Life And Times Of Peter Dunne

The unkind might talk of sinking ships, others could be more reminded of a loaded revolver left on the desk by his Cabinet colleagues as they closed the door behind them, now that the polls in Ohariu had confirmed he was no longer of much use to National. More>>

ALSO:

Gordon Campbell: On Labour’s Campaign Launch

One of the key motifs of Ardern’s speech was her repeated use of the phrase – “Now, what?” Cleverly, that looks like being Labour’s response to National’s ‘steady as it goes’ warning against not putting the economic ‘gains’ at risk. More>>

ALSO:

Lyndon Hood: Social Welfare, Explained

Speaking as someone who has seen better times and nowadays mostly operates by being really annoying and humiliating to deal with, I have some fellow feeling with the current system, so I’ll take this chance to set a few things straight.. More>>

ALSO:

 
 
 
 
 
 

LATEST HEADLINES

  • PARLIAMENT
  • POLITICS
  • REGIONAL
 
 

Featured InfoPages

Opening the Election