Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


Phase I Safety Study in Atopic Dermatitis

Genesis Research Announces Results of Phase I Safety Study in Atopic Dermatitis

Genesis Research and Development Corporation (NZSE / ASX: GEN) and SR Pharma plc (LSE: SPA) today announced the successful completion of a Phase I safety study of AVAC™ for the treatment of atopic dermatitis (also known as eczema) in children, which showed that AVAC was safe and well tolerated.

This trial of AVAC for atopic dermatitis in children follows a Phase I trial in adults completed in 2002. The present study, conducted in Wellington, involved 12 children aged 5 to 16 years.

All children received three intradermal injections of AVAC, at intervals of two weeks and were monitored closely for safety. Subjects were divided into four groups and were treated sequentially, with each dose group completing its assigned course of three injections before the next higher dose group commenced.

Injection site reactions were the major side effect of treatment, but there were no serious adverse events reported.

Although this small study was not designed to measure efficacy, clinical improvement in atopic dermatitis was noted in the majority of the children as measured by a standard scoring system for eczema.

Genesis Chief Executive Dr. Jim Watson says, “We are cautiously optimistic about this result. With the Phase I safety data in hand, we can now move ahead to our planned placebo-controlled Phase II trial, scheduled to start in the second quarter of 2003.

The Phase II trial will allow us to accurately determine any benefits resulting from AVAC treatment

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

Onetai Station: Overseas Investment Office Puts Ceol & Muir On Notice

The Overseas Investment Office (OIO) has issued a formal warning to Ceol & Muir and its owners, Argentinian brothers Rafael and Federico Grozovsky, for failing to provide complete and accurate information when they applied to buy Onetai Station in 2013. More>>

ALSO:

Tomorrow, The UN: Feds President Takes Reins At World Farming Body

Federated Farmers president Dr William Rolleston has been appointed acting president of the World Farmers’ Organisation (WFO) at a meeting in Geneva overnight. More>>

ALSO:

I Sing The Highway Electric: Charge Net NZ To Connect New Zealand

BMW is turning Middle Earth electric after today announcing a substantial contribution to the charging network Charge Net NZ. This landmark partnership will enable Kiwis to drive their electric vehicles (EVs) right across New Zealand through the installation of a fast charging highway stretching from Kaitaia to Invercargill. More>>

ALSO:

Watch This Space: Mahia Rocket Lab Launch Site Officially Opened

Economic Development Minster Steven Joyce today opened New Zealand’s first orbital launch site, Rocket Lab Launch Complex 1, on the Mahia Peninsula on the North Island’s east coast. More>>

Earlier:

Marketing Rocks!
Ig Nobel Award Winners Assess The Personality Of Rocks

A Massey University marketing lecturer has received the 2016 Ig Nobel Prize for economics for a research project that asked university students to describe the “brand personalities” of three rocks. More>>

ALSO:

Nurofen Promotion: Reckitt Benckiser To Plead Guilty To Misleading Ads

Reckitt Benckiser (New Zealand) intends to plead guilty to charges of misleading consumers over the way it promoted a range of Nurofen products, the Commerce Commission says. More>>

ALSO:

Get More From Scoop

 
 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news