Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


Xenotransplantation and the LCT trials in NZ


Xenotransplantation and the LCT trials in New Zealand

ONLINE BRIEFING: 1pm (NZT) Thursday 23 July

UPDATE: Living Cell Technologies, a New Zealand-based biotech firm, announced today that it is commencing trials on a potentially revolutionary diabetes treatment. 

The treatment will be based on xenotransplantation - the transplantation of animal cells, tissues or organs into human patients. In this case, LCT has been granted approval to transplant pig islet cells into sufferers of labile diabetes, in an attempt to cure the disease. 

The cells will be harvested from a unique, disease-free population of pigs isolated for nearly two centuries on the sub-Antarctic Auckland Islands. The pigs are now housed in a purpose-built, pathogen free breeding facility in Invercargill.

The trials have sparked interest globally and could potentially make New Zealand a significant player in this cutting-edge area of science. 

But what are the ramifications of this new technology? How safe is it, and what needs to be done to prove its worth?

Xenotransplantation is the transplantation of living cells, tissues or even organs from one species to another - in this case, from pigs to humans.  As such, it offers a potential treatment for people with heart, kidney or other organ failures, and chronic conditions like diabetes and Alzheimer's disease.  If perfected, it could mean that organ transplant waiting lists would become a thing of the past.

It also, however, raises complex scientific and ethical concerns. Religious groups and animal rights supporters have weighed in on the issue. Scientists have also voiced concerns around the possibility of viruses moving between species, the differing rate at which human and other organs age, and the consequences of changing animals' genes in this way.

Last month, after a comprehensive review and an agreement on revised conditions, New Zealand's Health Minister granted Living Cell Technologies (LCT) permission to conduct clinical trials of its diabetes treatment, DIABECELL®  What could the trials mean for New Zealand?  What is the science behind them?  And why is there a moratorium on xenotransplantation in other countries, including Australia?

In this Science Media Centre briefing the co-founder of LCT and a member of the International Xenotransplantation Association (IXA) will talk about xenotransplantation and the trials.  

SPEAKERS:

Prof Robert (Bob) Elliott, co-founder and Medical Director of Living Cell Technologies - Professor Elliott trained as a Paediatrician at Adelaide University and moved to New Zealand in 1970 to become the Foundation Professor, Department of Paediatrics at the University of Auckland. He is an Emeritus Professor of Child Health research, Professor of Paediatrics and a world leader in diabetes research. Professor Elliott is on the board of the New Zealand Child Health Foundation and the Wings Trust (a NZ trust for the treatment of alcohol and drug abuse). He is also patron of the NZ Cystic Fibrosis Foundation. In 1999 he was awarded a CNZM (a Companion of the New Zealand order of merit) for services to the community, and was the co-founder of LCT.

Prof Anthony D'Apice, Director of the Immunology Research Centre of St Vincent's Hospital, Melbourne - Prof D'Apice has been involved in xenotransplantation since 1989, primarily in the area of genetic modification of pigs to overcome the xenotransplant rejection process. He is also former President of The Aust & NZ Transplant Society and of the International Xenotransplantation Association, and a member of IXA Ethics Committee. Prof D'Apice is currently part of the group writing the IXA Consensus document on clinical islet xenotransplantation.

Assoc Prof Martin Wilkinson - Martin Wilkinson is an Associate Professor in the Department of Political Studies at the University of Auckland. He was Chair of the Bioethics Council 2006-2009 and Chair of the Council's working party on xenotransplantation in 2004-5. A political theorist by training, he has worked primarily in bioethics in the last 10 years. He is writing a book on the ethics of acquiring organs for transplantation.


ends

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

Fossils: Ancient Penguins Lived Alongside Dinosaurs?

Penguins are much older than previously thought and their evolution probably dates back to the days of the dinosaurs, according to research on the fossilised leg bone and toes of a giant ancient penguin found in rocks near Waipara, North Canterbury. More>>

No Voda/Sky: Commission Declines Clearance For Merger

The Commerce Commission has declined to grant clearance for the proposed merger of Sky Network Television and Vodafone New Zealand. More>>

ALSO:

EARLIER:

Power: IEA Report On New Zealand's Energy System

Outside of its largely low-carbon power sector, managing the economy’s energy intensity and greenhouse gas emissions while still remaining competitive and growing remains a challenge. More>>

ALSO:

NASA: Seven Earth-Size Planets Around A Single Star

NASA's Spitzer Space Telescope has revealed the first known system of seven Earth-size planets around a single star. Three of these planets are firmly located in the habitable zone, the area around the parent star where a rocky planet is most likely to have liquid water. More>>

ALSO:

Auckland Transport Case: Men Guilty Of Corruption And Bribery Will Spend Time In Jail

Two men who were found guilty of corruption and bribery in a Serious Fraud Office (SFO) trial have been sentenced in the Auckland High Court today... The pair are guilty of corruption and bribery offences relating to more than $1 million of bribes which took place between 2005 and 2013 at Rodney District Council and Auckland Transport. More>>

ALSO:

Hager Raid: Westpac Wrong To Release Bank Records To Police

The Privacy Commissioner has censured Westpac Banking Corp for releasing without a court order more than 10 months of bank records belonging to the political activist and journalist Nicky Hager during a police investigation into leaked information published in Hager's 2014 pre-election book, 'Dirty Politics'. More>>

ALSO:

EARLIER:

Get More From Scoop

 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news