Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


World’s First Particle-By-Particle Charge Analysis Method

Media Release
Izon Releases World’s First Particle-By-Particle Charge Analysis Method

New particle charge analysis method addresses gap in nanomedicine research

Christchurch, NEW ZEALAND, 6 December 2012 –

Nanotechnology instrument manufacturer Izon Science (www.izon.com) has released the first commercially available method to simultaneously measure the charge and size of nano- and submicron particles on a particle by particle basis. This innovative high resolution analysis developed for Izon’s qNano platform will provide researchers with a new tool to better understand and advance their work in a range of fields, including drug delivery, diagnostics and exosomes and microvesicles.

Hans van der Voorn, Executive Chairman of Izon Science says, “Researchers can now use a qNano to distinguish particles by charge as well as size. This unique analysis capability will enable researchers to accurately measure and understand their samples in a way not previously possible. We anticipate that this detailed information will lead to better experimental results and more acceptance of lab based nanomedicine innovations for clinical use.”

Researchers working in the field of nanoparticle and liposome based drug delivery will find particular interest and benefits from Izon’s new analysis capability. This is because the therapeutic delivery efficacy, circulation time, effluent pathway, localized accumulation, cellular uptake, drug release profile and potential toxicity of drug delivery particles is mainly dependent on their size, charge, and concentration. The Izon qNano now provides the ability to accurately measure all of these properties.

The new method measures the electrophoretic mobility of each particle as it traverses Izon’s tunable elastic pore. Very fine pressure control, via a new Variable Pressure Module (VPM), is used to regulate and optimize the forces acting on the particles, improving the accuracy of zeta-potential measurements. Izon’s new methodology also allows particle size to be analyzed at the same time, enabling, for the first time, an accurate measurement of both particle charge (zeta-potential) and size distribution. As individual particles are measured and counted, the numbers of particles for each charge and size fraction are also reported.

This newly available method of simultaneously measuring both the charge and size of individual particles offers much higher resolution for particle characterization than existing techniques, which are generally limited to measuring the average of either but not both properties at once. The qNano’s ability to accurately measure the charge and size distribution and number distribution of particle systems is likely to become essential for nanomedicine researchers wanting to gain regulatory approvals for medical use.

A beta version of the method was presented and discussed at the recent Izon Micro- and Nano-particle research symposium held at Izon’s new European headquarters at the Oxford Science Park.

Hans van der Voorn says, “It is always great to be an active part of new and exciting research. Learning about the current needs of academic researchers and working with them to provide new tools is integral to Izon’s goals. Having the researchers working with us helped with method development and application of this new technique. I expect that new applications that we wouldn’t think of will continue be invented and developed by qNano users.”

The new method is available through a modular hardware and software upgrade for existing users, or as a standard feature, which comes with Izon’s qNano particle analysis system.

– ENDS –


About Izon Science:
Izon Science has developed the world’s first nanopore based measurement system available for general use. Izon’s instruments are used for precise measurement and analysis of individual particles across a wide range of scientific fields including bionanotechnology, nanomedicine, vaccinology, microbiology, biomedical research, environmental science, and particle based nanoscience. Izon originated in New Zealand and now sells its products in 34 countries. It has its European headquarters in Oxford, UK and its US headquarters are in Cambridge, MA.
Website: http://www.izon.com

Follow Us:
Facebook: http://www.facebook.com/izonscience
Twitter: http://www.twitter.com/izonscience

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

ETS Review: Modelling Documents Released

Three technical documents are being released to help New Zealanders engage with the Emissions Trading Scheme (ETS) review, Climate Change Minister Paula Bennett says. More>>

ALSO:

Northland: Govt Plan Targets Transport, Web, Maori Assets

The government has released a 10-year plan to attract investors and lift economic growth in Northland, a region that perennially underperforms the rest of the country even while being endowed with natural beauty, productive land, minerals, a potential workforce, scope for manufacturing, forestry and aquaculture, and proximity to Auckland. More>>

ALSO:

Statistics: Unemployment Rate Falls To 5.3 Percent

The unemployment rate fell to 5.3 percent in the December 2015 quarter (from 6.0 percent), Statistics New Zealand said today. This is the lowest unemployment rate since March 2009. There were 16,000 fewer people unemployed than in the September ... More>>

ALSO:

Employment: Labour Urges Talley’s To End AFFCO Lockout

Labour has urged Talley’s to resolve the ongoing industrial dispute with AFFCO workers which is having a severe effect on the employees, their families and their communities, Labour’s Workplace Relations spokesperson Iain Lees-Galloway says. More>>

ALSO:

Three Kings: Govt To Oppose Appeal Blocking $1.2B Auckland Housing Plan

Environment Minister Nick Smith and Housing New Zealand have joined legal proceedings in support of Auckland Council and Fletcher Building opposing a bid by community groups to only allow low-rise housing in a $1.2 billion housing redevelopment on the disused site of the Three Kings quarry. More>>

ALSO:

Transport: Jetstar Expands Regional Network With Three New Routes

More New Zealanders than ever before will have access to Jetstar’s affordable flights when new services take off today from Auckland to New Plymouth and Palmerston North, and Nelson to Wellington. More>>

ALSO:

Get More From Scoop

 
 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news