Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


World’s First Particle-By-Particle Charge Analysis Method

Media Release
Izon Releases World’s First Particle-By-Particle Charge Analysis Method

New particle charge analysis method addresses gap in nanomedicine research

Christchurch, NEW ZEALAND, 6 December 2012 –

Nanotechnology instrument manufacturer Izon Science (www.izon.com) has released the first commercially available method to simultaneously measure the charge and size of nano- and submicron particles on a particle by particle basis. This innovative high resolution analysis developed for Izon’s qNano platform will provide researchers with a new tool to better understand and advance their work in a range of fields, including drug delivery, diagnostics and exosomes and microvesicles.

Hans van der Voorn, Executive Chairman of Izon Science says, “Researchers can now use a qNano to distinguish particles by charge as well as size. This unique analysis capability will enable researchers to accurately measure and understand their samples in a way not previously possible. We anticipate that this detailed information will lead to better experimental results and more acceptance of lab based nanomedicine innovations for clinical use.”

Researchers working in the field of nanoparticle and liposome based drug delivery will find particular interest and benefits from Izon’s new analysis capability. This is because the therapeutic delivery efficacy, circulation time, effluent pathway, localized accumulation, cellular uptake, drug release profile and potential toxicity of drug delivery particles is mainly dependent on their size, charge, and concentration. The Izon qNano now provides the ability to accurately measure all of these properties.

The new method measures the electrophoretic mobility of each particle as it traverses Izon’s tunable elastic pore. Very fine pressure control, via a new Variable Pressure Module (VPM), is used to regulate and optimize the forces acting on the particles, improving the accuracy of zeta-potential measurements. Izon’s new methodology also allows particle size to be analyzed at the same time, enabling, for the first time, an accurate measurement of both particle charge (zeta-potential) and size distribution. As individual particles are measured and counted, the numbers of particles for each charge and size fraction are also reported.

This newly available method of simultaneously measuring both the charge and size of individual particles offers much higher resolution for particle characterization than existing techniques, which are generally limited to measuring the average of either but not both properties at once. The qNano’s ability to accurately measure the charge and size distribution and number distribution of particle systems is likely to become essential for nanomedicine researchers wanting to gain regulatory approvals for medical use.

A beta version of the method was presented and discussed at the recent Izon Micro- and Nano-particle research symposium held at Izon’s new European headquarters at the Oxford Science Park.

Hans van der Voorn says, “It is always great to be an active part of new and exciting research. Learning about the current needs of academic researchers and working with them to provide new tools is integral to Izon’s goals. Having the researchers working with us helped with method development and application of this new technique. I expect that new applications that we wouldn’t think of will continue be invented and developed by qNano users.”

The new method is available through a modular hardware and software upgrade for existing users, or as a standard feature, which comes with Izon’s qNano particle analysis system.

– ENDS –


About Izon Science:
Izon Science has developed the world’s first nanopore based measurement system available for general use. Izon’s instruments are used for precise measurement and analysis of individual particles across a wide range of scientific fields including bionanotechnology, nanomedicine, vaccinology, microbiology, biomedical research, environmental science, and particle based nanoscience. Izon originated in New Zealand and now sells its products in 34 countries. It has its European headquarters in Oxford, UK and its US headquarters are in Cambridge, MA.
Website: http://www.izon.com

Follow Us:
Facebook: http://www.facebook.com/izonscience
Twitter: http://www.twitter.com/izonscience

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

Scoop Business: NZ Dollar Falls To 3-Year Low As Investors Favour Greenback

The New Zealand dollar fell to its lowest in more than three years as investors sold euro and bought US dollars, weakening other currencies against the greenback. More>>

ALSO:

Scoop Business: NZ Govt Operating Deficit Smaller Than Expected

The New Zealand’s government’s operating deficit was smaller than expected in the first five months of the financial year as a clampdown on expenditure managed to offset a shortfall in the tax-take from last month’s forecast. More>>

ALSO:

0.8 Percent Annually:
NZ Inflation Falls Below RBNZ's Target

New Zealand's annual pace of inflation slowed to below the Reserve Bank's target band in the final three months of the year, giving governor Graeme Wheeler more room to keep the benchmark interest rate lower for longer.More>>

ALSO:

NASA, NOAA: Find 2014 Warmest Year In Modern Record

Since 1880, Earth’s average surface temperature has warmed by about 1.4 degrees Fahrenheit (0.8 degrees Celsius), a trend that is largely driven by the increase in carbon dioxide and other human emissions into the planet’s atmosphere. The majority of that warming has occurred in the past three decades. More>>

ALSO:

Scoop Business: New Zealand’s Reserve Bank Named Central Bank Of The Year

The Reserve Bank of New Zealand’s efforts to stifle house price inflation by using new policy tools has seen the institution named Central Bank of the year by Central Banking Publications, a publisher specialising in global central banking practice. More>>

ALSO:

Science Media Centre: Viral Science And Another 'Big Dry'?

"Potentially, if there is no significant rainfall for the next month or so, we could be heading into one of the worst nation-wide droughts we’ve seen for some time," warns NIWA principal climate scientist Dr Andrew Tait. More>>

ALSO:

Get More From Scoop

 
 
Standards New Zealand

Standards New Zealand
 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news