Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


Recognition for tissue engineering success


26 November 2013


Recognition for tissue engineering success


Professor Neil Broom, winner of this year’s MacDiarmid Medal from the Royal Society of New Zealand, used skills and techniques honed in metallurgy and applied them to solve complex problems of biological tissue structure.

Professor Broom teaches engineering materials in the Department of Chemical and Materials Engineering at the University of Auckland’s Faculty of Engineering, but his entire research focus is on soft tissue.

He has developed novel experimental approaches that have led to major improvements in bio-prosthetic heart valve function, new insights into both joint tissue structure and osteoarthritis and the structural and mechanical basis of intervertebral disc prolapse.

Professor Broom’s initial training in metallurgy was applied successfully to experimental tissue mechanics and has earned him an international reputation in this field.

“The MacDiarmid medal is a humbling tribute to the work of our very small laboratory,” says Professor Broom who leads the Experimental Tissue Mechanics Laboratory. “I’m hugely gratified to see the work of so many students who work with me, also recognised by this award.”

“We have a small lab within the department, and students come here with little academic preparation for working with soft tissues, and yet we have achieved incredibly well on an international scale,” he says.

He made particular mention of his colleague, Dr Ashvin Thambyah who came to do post-doctoral studies from the National University of Singapore in 2005 and has stayed on to become a senior lecturer in the Department.

“We have worked together on this research and leading the laboratory,” he says.

Dean of the Faculty of Engineering, Professor Nic Smith says, “This is a fantastic achievement for Neil and his team and a great acknowledgement of the wonderful contribution he has made in the area of bio-materials over the course of his distinguished career. As the human relevance of engineering becomes more and more significant Neil’s work is an exemplar.”

Professor Broom’s earlier aortic valve research fundamentally altered the bio-prosthetic valve industry world-wide with most leading manufacturers now employing his low-pressure tissue stabilisation treatment described in his research publications to optimise valve leaflet flexibility and thus enhance durability in vivo.

His key achievements in joint-tissue research include the development of new collagen-based physical models for cartilage to account for the structural weakening occurring in the cartilage matrix arising from both early degeneration and trauma.

Professor Broom has provided rigorous, experimentally-based analyses of both the role of the strain-limiting articular surface, and the biomechanically critical junction region between the compliant cartilage and bone in its physiological state.

He and his team have produced evidence of primary bone formation beneath the still-intact cartilage adjacent to lesion sites thus clarifying the elusive pre-osteoarthritic state.

His research has produced a structural “gold standard” for the international community of ‘tissue engineering’ researchers, challenging them to ‘engineer’ matrices that are biomechanically viable.

Professor Broom’s most recent research, in collaboration with spinal surgeon Dr Peter Robertson, has focussed on the intervertebral disc (IVD). He and his team have developed new structural insights into the micro-anatomy of the disc wall to explain the mechanical basis of annular disruption and prolapse, these being linked to two of the most prevalent and debilitating clinical conditions of the modern world - low back and radicular pain.

He has shown experimentally how nucleus material interacts with the disc wall and endplate, and how combinations of flexion, torsion, and rate of loading can cause nuclear fragments to migrate out through the wall and cause prolapse.

This pioneering research is the first published integration of disc micro-architecture, functional posture, and loading rate, with susceptibility to failure.

ENDS

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

Scoop Business: Alex Swney Pleads Guilty To $2.5M Fraud Charge

Alex Swney, former chief executive of the Auckland city centre business association Heart of the City, has pleaded guilty to dishonestly using documents to obtain $2.5 million. More>>

ALSO:

Petrol Burns Prices: Second Consecutive Quarterly Fall For CPI

The consumers price index (CPI) fell 0.3 percent in the March 2015 quarter, following a 0.2 percent fall in the December 2014 quarter, Statistics New Zealand said today. The last time the CPI showed two consecutive quarterly falls was in the December 1998 and March 1999 quarters. More>>

ALSO:

Scoop Business: NZ Broadcasters Launch Battle Against Global Mode ISPs

New Zealand broadcasters have confirmed they’ve launched legal proceedings against internet service providers who give customers’ access to “global mode”, which allows customers access to offshore online content, claiming it breaches the local content providers’ copyright. More>>

ALSO:

Sanford: Closure Of Christchurch Mussel Processing Plant Confirmed

The decision comes after a period of consultation with the 232 staff employed at the Riccarton site, who were told on 9 April that Sanford was considering the future of mussel processing in Christchurch. Recent weather patterns had impacted on natural spat (offspring) supply... More>>

ALSO:

Price Of Cheese: Dairy Product Prices Fall To The Lowest This Year

Dairy product prices fell in the latest GlobalDairyTrade auction, hitting the lowest level in the 2015 auctions so far, as prices for milk powder and butter slid amid concern about the outlook for commodities. More>>

ALSO:

Houston, We Have An Air Route: Air New Zealand To Fly Direct To The Heart Of Texas

Air New Zealand will fly its completely refitted Boeing 777-200 aircraft between Auckland and Houston up to five times a week opening up the state of Texas as well as popular nearby tourist states such as Louisiana and Florida. More>>

ALSO:

Scoop Business: Reserve Bank’s Spencer Calls On Govt To Rethink Housing Tax

The Reserve Bank has urged the government to take another look at a capital gains tax on investment in housing, allow increased high-density development and cut red tape for planning consents to address an over-heated Auckland property market. More>>

ALSO:

Get More From Scoop

 
 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news