Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


Waikato science students tackle cancer and memory research

25 February, 2014

Waikato science students tackle cancer and memory research


Click for big version.

Biomedical research at Waikato University: From back left, Dr Michael Jameson, Dr Steven Bird, Greg Jacobson and Dr Logan Voss. From front left, Laura Bell, Dr Linda Peters, Kirsty Mayall and Stephen Evans.

Preventing breast cancer, reducing the toxicity of radiotherapy and chemotherapy side effects, and analysing memory function during anaesthesia, were the topics for three students from the University of Waikato, who have just completed summer studentships.

Laura Bell, Kirsty Mayall and Stephen Evans were each awarded a Waikato Clinical School Summer Studentship worth $5000. Laura and Kirsty are about to embark on their second year of a Master of Science (MSc), while Stephen is in his first year of a PhD. All three students are focusing on biomedical science and will each take their studentship research topic to the next level throughout 2014, as part of their degree.

Breast cancer prevention

Former Hamilton Girls’ High student Kirsty Mayall’s studentship research focuses on breast cancer prevention, and is co-supervised by University of Waikato lecturer and molecular geneticist Dr Linda Peters, and medical research scientist and consultant oncologist Dr Michael Jameson from the Waikato Hospital’s Oncology department.

“Selenium (Se) is an essential trace mineral that has critical roles in maintaining health in humans. Depending on the concentration and type of selenium, it can cause or prevent breast cancer,” says Kirsty.

The aim of this study is to test two different types of selenium at three concentrations each in human breast cancer cells that carry the BRCA1 mutation (an inherited breast and ovarian cancer gene).

“During my MSc I’ll be looking at the different concentrations of selenium on the breast cancer cell lines and what dose is lethal for the cells. From there we’ll investigate what dose is most effective at reducing the levels of DNA damage present in the cells.”

Reducing toxicity of radiotherapy and chemotherapy

Stephen Evans is supervised by Dr Jameson and Waikato University’s Dr Steve Bird, with additional support from Dr Peters and Dr Ray Cursons.

His study will also focus on selenium, but instead of cancer prevention, he will look at reducing the negative effects of cancer treatment.

“High doses of selenium have been shown to reduce chemotherapy and radiotherapy-induced toxicities towards blood forming stem cells in both animal and human studies. My project examines the effects of selenium on the growth of such cells when they are exposed to these toxic cancer treatments,” says Stephen.

Memory function during anaesthesia

Laura Bell was originally inspired to study biology by her Year 12 Hillcrest High School science teacher. Her research focuses on the effects of general anaesthetics on a patient’s memory and is supervised by Dr Peters alongside Dr Logan Voss from the Anaesthesia Department at Waikato Hospital.

“The mechanism by which anaesthetics disrupt memory is not well understood, but is likely to involve an interruption to gene expression and protein synthesis pathways,” says Laura.

Laura explains that previous studies have focused on the effect of anaesthetics in the hippocampal area of the brain. However, the cerebral cortex is also an important site for memory and this is the area that she will be investigating.

“In this study we will investigate anaesthetic effects on genes related to memory in the brain. In particular, we will determine whether general anaesthetics alter expression of genes related to signalling mechanisms.”

Collaboration
The projects provide further collaborative research links between staff from the University of Waikato and Waikato Hospital, which Dr Peters says is exciting for the development of biomedical science research at the University.

ENDS

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

Company Results: Air NZ Rides The Tourism Boom With Record Full-Year Earnings

Air New Zealand has ridden the tourism boom and staved off increased competition to deliver the best full-year earnings in its 76-year history. More>>

ALSO:

New PGP: Sheep Milk Industry Gets $12.6M Crown Funding

The Sheep - Horizon Three programme aims to develop "a market driven, end-to-end value chain generating annual revenues of between $200 million and $700 million by 2030," according to a joint statement. More>>

ALSO:

Half Full: Fonterra Raises Forecast Milk Price

Fonterra Co-operative Group Limited today increased its 2016/17 forecast Farmgate Milk Price by 50 cents to $4.75 per kgMS. When combined with the forecast earnings per share range for the 2017 financial year of 50 to 60 cents, the total payout available to farmers in the current season is forecast to be $5.25 to $5.35 before retentions. More>>

ALSO:

Keep Digging: Seabed Ironsands Miner TransTasman Tries Again

The first company to attempt to gain a resource consent to mine ironsands from the ocean floor in New Zealand's Exclusive Economic Zone has lodged a new application containing fresh scientific and other evidence it hopes will persuade regulators after their initial application was turned down in 2014. More>>

Wool Pulled: Duvets Sold As ‘Premium Alpaca’ Mostly Sheep’s Wool

Rotorua business Budge Collection Limited (Budge) and sole director, Sun Dong Kim, were convicted and fined a total of $71,250 in Auckland District Court after each pleading guilty to four charges of misrepresenting how much alpaca fibre was in their duvets. More>>

Reserve Bank: Labour Calls For Monetary Policy To Expand Goals

Labour's comments follow a speech today by RBNZ governor Graeme Wheeler in which Wheeler sought to answer critics who variously say he should stop lowering interest rates, lower them faster, or that inflation-targeting should no longer be the primary goal of the central bank's activities. More>>

ALSO:

BSA Extension And Sunday Morning Ads: Digital Convergence Bill Captures Online Content

Broadcasting Minister Amy Adams has today announced the Government’s plans to update the Broadcasting Act to better reflect today’s converged market... The Government considered four areas as part of its review into content regulation: classification requirements, advertising restrictions, election programming and contestable funding. More>>

ALSO:

Get More From Scoop

 
 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news