Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search


Link between hypertension and vitamin D deficiency

Study locks in link between hypertension and vitamin D deficiency

A new genetic study led by University of South Australia epidemiologist Professor Elina Hyppönen has confirmed a causal link between high blood pressure (hypertension) and deficiencies in vitamin D.

The findings just published in the Lancet Diabetes and Endocrinology journal, drew on a sample of more than 146,000 records to assess the association.

“We set up a Mendelian randomisation study using genetic data from the D-CarDia collaboration involving more than 140,000 individuals of European ancestry from across Europe and North America,” Prof Hyppönen says.

“We used two common genetic variants that affect circulating 25-hydroxyvitamin D concentrations, which are generally used to determine a person’s vitamin D status, to measure the causal effect between vitamin D status and blood pressure and hypertension risk.

“And what we found was that for each 10 per cent increase in 25-hydroxyvitamin D concentration there were drops in both diastolic and systolic blood pressure.

“Statistically the association translated to just over an eight percent decrease in the odds of developing hypertension.”

Prof Hyppönen says that while there have been some small scale studies and randomised trials, until now, a direct causal link between vitamin D and a lowering of blood pressure has not been shown.

“These findings may have important implications to individuals who are vitamin D deficient,” Prof Hyppönen believes. “The potential to prevent and reduce high blood pressure with vitamin D in place of more expensive medications is certainly something researchers can now usefully explore in greater depth.”

According to Prof Hyppönen while Mendelian randomisation helps to determine cause and effect by using genetic data and avoiding bias, there is always a possibility that the findings could occur by chance.

“What will be really important is an independent replication of this study,” Prof Hyppönen says.

“And to advance the work further, we need to do more research using randomised controlled studies to look at and confirm causality and importantly assess the clinical benefits of vitamin D supplements and dosage levels.”

This significant research into the relationship between vitamin D and hypertension was funded by the British Heart Foundation, UK Medical Research Council, and Academy of Finland.

Prof Hyppönen is a member of UniSA’s School of Population Health working at the South Australian Health and Medical Research Institute.


© Scoop Media

Business Headlines | Sci-Tech Headlines


Hourly Wage Gap Grows: Gender Pay Gap Still Fixed At Fourteen Percent

“The totally unchanged pay gap is a slap in the face for women, families and the economy,” says Coalition spokesperson, Angela McLeod. Even worse, Māori and Pacific women face an outrageous pay gap of 28% and 33% when compared with the pay packets of Pākehā men. More>>


Housing: English On Housing Affordability And The Economy

"Long lead times in the planning process tend to drive prices higher in the upswing of the housing cycle. And those lead times increase the risk that eight years later, when additional supply arrives, the demand shock that spurred the additional supply has reversed. The resulting excess supply could produce a price crash..." More>>


Sweet Health: Sugary Drinks Banned From Hospitals And Health Boards

All hospitals and DHBs are expected to kick sugary drinks out of their premises. University of Auckland researcher, Dr Gerhard Sundborn who also heads public health advocacy group “FIZZ”, says he welcomes the initiative. More>>


NASA: Evidence Of Liquid Water On Today's Mars

Using an imaging spectrometer on MRO, researchers detected signatures of hydrated minerals on slopes where mysterious streaks are seen on the Red Planet. These darkish streaks appear to ebb and flow over time. More>>


Bird Brains: Robins Can Just Be Generally Clever

Research from Victoria University of Wellington has revealed that birds may possess a ‘general intelligence’ similar to humans, with some individuals able to excel in multiple cognitive tests. More>>


Psa-V: Positive Result On Whangarei Kiwifruit Orchard

Kiwifruit Vine Health (KVH) has received a Psa-V positive test result on Hort16A and male vines on a kiwifruit orchard in Whangarei. This is the first confirmed case of Psa-V on an orchard in the Whangarei region. More>>

Regional Accents: Are Microbes The Key To Geographical Differences In Wine?

A new study of six of New Zealand’s major wine-growing regions has found that differences in flavour and aroma of wine from different areas may depend more on microbes than was previously thought. More>>


Science: AgResearch To Cut Science Staff In Areas Of 'Reduced Demand'

“We are therefore consulting with our staff from today on a proposal to reduce science staff in areas of shrinking demand. Combined with recruitment planned in areas of growing demand, this would mean a net reduction of 15 scientists and 41 technicians at AgResearch in the 2015/16 year." More>>


Get More From Scoop

Search Scoop  
Powered by Vodafone
NZ independent news