Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search

 


Link between hypertension and vitamin D deficiency

Study locks in link between hypertension and vitamin D deficiency

A new genetic study led by University of South Australia epidemiologist Professor Elina Hyppönen has confirmed a causal link between high blood pressure (hypertension) and deficiencies in vitamin D.

The findings just published in the Lancet Diabetes and Endocrinology journal, drew on a sample of more than 146,000 records to assess the association.

“We set up a Mendelian randomisation study using genetic data from the D-CarDia collaboration involving more than 140,000 individuals of European ancestry from across Europe and North America,” Prof Hyppönen says.

“We used two common genetic variants that affect circulating 25-hydroxyvitamin D concentrations, which are generally used to determine a person’s vitamin D status, to measure the causal effect between vitamin D status and blood pressure and hypertension risk.

“And what we found was that for each 10 per cent increase in 25-hydroxyvitamin D concentration there were drops in both diastolic and systolic blood pressure.

“Statistically the association translated to just over an eight percent decrease in the odds of developing hypertension.”

Prof Hyppönen says that while there have been some small scale studies and randomised trials, until now, a direct causal link between vitamin D and a lowering of blood pressure has not been shown.

“These findings may have important implications to individuals who are vitamin D deficient,” Prof Hyppönen believes. “The potential to prevent and reduce high blood pressure with vitamin D in place of more expensive medications is certainly something researchers can now usefully explore in greater depth.”

According to Prof Hyppönen while Mendelian randomisation helps to determine cause and effect by using genetic data and avoiding bias, there is always a possibility that the findings could occur by chance.

“What will be really important is an independent replication of this study,” Prof Hyppönen says.

“And to advance the work further, we need to do more research using randomised controlled studies to look at and confirm causality and importantly assess the clinical benefits of vitamin D supplements and dosage levels.”

This significant research into the relationship between vitamin D and hypertension was funded by the British Heart Foundation, UK Medical Research Council, and Academy of Finland.

Prof Hyppönen is a member of UniSA’s School of Population Health working at the South Australian Health and Medical Research Institute.

ends

© Scoop Media

 
 
 
 
 
Business Headlines | Sci-Tech Headlines

 

SOE Results: TVNZ Lifts Annual Profit 25% On Flat Ad Revenue, Quits Igloo

Television New Zealand, the state-owned broadcaster, lifted annual profit 25 percent, ahead of forecast and despite a dip in advertising revenue, while quitting its stake in the pay-TV Igloo joint venture with Sky Network Television. More>>

ALSO:

Insurers Up For More Payouts: Chch Property Investor Wins Policy Appeal In Supreme Court

Ridgecrest NZ, a property investor, has won an appeal in the Supreme Court over insurance cover provided by IAG New Zealand for a Christchurch building damaged in four successive earthquakes. More>>

ALSO:

Other Cases:

Royal Society: Review Finds Community Water Fluoridation Safe And Effective

A review of the scientific evidence for and against the efficacy and safety of fluoridation of public water supplies has found that the levels of fluoridation used in New Zealand create no health risks and provide protection against tooth decay. More>>

ALSO:

Scoop Business: Croxley Calls Time On NZ Production In Face Of Cheap Imports

Croxley Stationery, whose stationery brands include Olympic, Warwick and Collins, plans to cease manufacturing in New Zealand because it has struggled to compete with lower-cost imports in a market where the printed word is giving way to electronic communications. More>>

ALSO:

Prefu Roundup: Forecasts Revised, Surplus Intact

The National government heads into the election with its Budget surplus target broadly intact, delivering a set of economic and fiscal forecasts marginally revised from May to reflect weaker commodity prices and a lower tax take. More>>

ALSO:

Convention Centre: Major New SkyCity Hotel And Laneway For Auckland

Today SKYCITY Entertainment Group Limited revealed plans to build a new hotel and pedestrian laneway of bars, restaurants and boutique shopping on land it owns in the Nelson and Hobson Streets block, expanding the SKYCITY Entertainment Precinct. More>>

ALSO:

Get More From Scoop

 
 
Computer Power Plus

Standards New Zealand

Standards New Zealand
 
 
 
 
 
 
 
 
Sci-Tech
Search Scoop  
 
 
Powered by Vodafone
NZ independent news