News Video | Policy | GPs | Hospitals | Medical | Mental Health | Welfare | Search

 

University Of Auckland Leads Project To Combat RSV, Flu By Applying Covid-19 Lessons

New Zealand’s expertise tracking Covid-19 is being applied to influenza and respiratory syncytial virus (RSV) in a $9.8 million project to learn how to stop the spread of respiratory viruses.

The two-year project, Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance V (SHIVERS-V), is led by the University of Auckland in collaboration with the Institute of Environmental Science and Research (ESR) and features genomic testing of viruses, the detective work which became routine during the Covid-19 pandemic.

Researchers will analyse thousands of swabs from patients with respiratory illnesses to discover how respiratory viruses enter and spread within Aotearoa. This will help scientists model outbreaks and, most importantly, help design strategies to prevent them.

New Zealand is uniquely suited to examine the re-introduction and transmission of respiratory viruses like influenza and RSV. The success of New Zealand’s Covid-19 measures has created a novel environment for this ambitious project, and its well-developed systems for tracking health data facilitate population-level research.

The current RSV epidemic is part of a respiratory-disease environment unlike any New Zealand has seen before. Sick children are filling hospital wards after Covid-19 social distancing and lockdown restrictions blocked the development of natural immunity to RSV. Scientists are also watching to see what happens next with influenza after Covid restrictions virtually eliminated the disease.

“As border restrictions are likely eased over the next two years, we will face a resurgence of respiratory viruses,” says Professor Nikki Turner, medical director of the University of Auckland’s Immunisation Advisory Centre (IMAC). “Understanding the viruses’ patterns will help us predict and mitigate outbreaks to help protect whānau and communities in this new post-Covid world.”

South Auckland is a focus of the research because of the social deprivation that exacerbates the spread of disease and the risk that the international airport will serve as a vector for disease transmission. Swabs of children at kohanga reo and early childhood learning centres will help to establish baseline rates of respiratory diseases.

Swab tests will also occur at doctors’ offices in Wellington and Auckland and the emergency department of Middlemore Hospital. People in managed isolation facilities will be tested for respiratory diseases additional to Covid-19.

Professor Turner and Professor Peter McIntyre, who is affiliated with both the Otago and Auckland universities, will helm the study. After leading previous SHIVERS projects starting in 2012 in Auckland and Wellington, virologist Sue Huang of ESR will play a key role. “Expanding the SHIVERS programme with information from the impact of closed borders is an important next step in helping tackle the viruses in a post-Covid world,” says Dr Huang.

Epidemiologic, clinical, and genomic information will be combined in the same way ESR tracks Covid-19 outbreaks. The University of Auckland’s Professor Shaun Hendy, known for his Covid-19 modelling, will do similar work for this new project.

The SHIVERS-V research will cover:

· The impact of border closures and lockdowns on respiratory virus transmission
· The influence of travel on the spread of influenza, RSV, and other respiratory viruses
· The capability to forecast how respiratory viruses behave in future winter seasons
· How a year of minimal exposure to respiratory viruses affected subsequent transmission and disease among preschool children

University of Otago evolutionary virologist Dr Jemma Geoghegan and Dr Joep de Ligt of ESR will genetically type viruses. Associate Professor Cass Byrnes of the University of Auckland, and Dr Adrian Trenholme, a pediatrician at Middlemore Hospital, will track the severity of respiratory infections in young children.

“This is crucial work,” says Professor Turner. “The RSV epidemic is particularly concerning because of its impact on those who are most vulnerable: our tamariki, our elderly, those with significant medical problems, those in poor housing, and particularly for our Māori and Pacific communities.”

This project is funded by the U.S.-based Flu Lab, which envisions a world free from the dangers of influenza. To achieve this, Flu Lab seeks out high-impact opportunities and makes grants and investments to create actionable knowledge and advance solutions to pressing influenza challenges. It is funding the project through UniServices, a wholly-owned company of the University of Auckland focusing on knowledge transfer and research commercialisation. Previous SHIVERS work in New Zealand was funded by the U.S. government.

© Scoop Media

 
 
 
Culture Headlines | Health Headlines | Education Headlines

 


Howard Davis: Emerald Fennell's Promising Young Woman'


The Guardian needed not one, but three reviews to do justice to Fennell's unsettling approach, which indicates exactly how ambiguous and controversial its message really is. More>>


Howard Davis: Jill Trevelyan's Rita Angus

Although Angus has become one of Aotearoa’s best-loved painters, the story of her life remained little known and poorly understood before Jill Trevelyan's acclaimed and revelatory biography, which won the Non Fiction Award at the Montana New Zealand Book Awards in 2009, and has now been republished by Te Papa press. More>>

Howard Davis: The Back of the Painting

Painting conservators are the forensic pathologists of the art world. While they cannot bring their subjects back to life, they do provide fascinating insights into the precise circumstances of a painting's creation, its material authenticity, and constructive methodology. More>>


Howard Davis: Black Panthers on the Prowl

A passionate and gripping political drama from Shaka King, this is an informative and instructive tale of human frailty that centers around the charismatic Chicago Black Panther leader Fred Hampton, who was murdered at the age of twenty-one during a police raid. More>>

Howard Davis: Controlling the High Ground

Stephen Johnson's raw and angry film not only poses important questions with scrupulous authenticity, but also provides a timely reminder of the genocidal consequences of casual bigotry and xenophobia. More>>

Howard Davis: Dryzabone - Robert Conolly's The Dry

After the terrible devastation caused by last year’s bushfires, which prompted hundreds of Australians to shelter in the ocean to escape incineration and destroyed uncountable amounts of wildlife, The Dry has been released during a totally different kind of dry spell. More>>


Howard Davis: Hit the Road, Jack - Chloé Zhao's Nomadland

Nomadland is perhaps the ultimately 'road' movie as it follows a group of dispossessed and disenfranchised vagabonds who find a form of communal refuge in camp sites and trailer parks after the economic contraction of 2008. More>>

 
 
 
 
 
 

LATEST HEADLINES

  • CULTURE
  • HEALTH
  • EDUCATION
 
 
  • Wellington
  • Christchurch
  • Auckland