Video | Business Headlines | Internet | Science | Scientific Ethics | Technology | Search


Cannabis compound may reduce psychosis

Cannabis compound may reduce psychosis

1 December 2005

Cannabis, a drug believed to increase the risk of psychosis in users, contains a compound that may be able to reverse psychotic behaviour, Monash researchers have found.

The scientists have identified a chemical compound in cannabis -- cannabidiol -- that has been found to reverse drug-induced behavioural disturbances in mice.

Ms Leonora Long, a PhD researcher at the university's Victorian College of Pharmacy, said consumption of cannabis had been associated with an increased risk of developing psychosis because of the effects of tetrahydrocannabinol (THC), which creates the "high" observed in humans.

"Our previous research has shown that cannabis compounds such as THC, that can produce psychosis in humans, also produce behavioural deficiencies in rodents that mimic symptoms of psychosis," Ms Long said.

"Now, it has been shown in our animal tests that the cannabidiol compound reverses these types of behavioural deficiencies.

"This could mean that cannabidiol may reverse the symptoms of psychosis in humans," she said.

"The interesting thing is, that you have these two compounds in the cannabis plant that produce opposing effects. One is liable to produce psychotic symptoms, while the other may be protective against psychosis.

"Cannabidiol may also help alleviate the symptoms of epilepsy and also pain associated with inflammatory disorders such as multiple sclerosis," Ms Long said.

The Monash researchers now plan to investigate the effects of cannabidiol and THC together in rats and mice, to see how the two compounds interact, and to mimic human consumption of cannabis.

Ms Long, Dr David Taylor and Dr Dan Malone of the Department of Pharmaceutical Biology and Pharmacology, have published their findings in the journal Neuropsychopharmacology.


© Scoop Media

Business Headlines | Sci-Tech Headlines


Infrastructure Commission: Te Waihanga Releases Report On Water Infrastructure

The New Zealand Infrastructure Commission, Te Waihanga’s latest discussion document highlights the importance of current reforms in the water sector. Its State of Play discussion document about water infrastructure is one of a series looking at the ... More>>

Sci-Tech: Perseverance Rover Lands On Mars – Expert Reaction

NASA has landed a car-sized rover on the red planet to search for signs of past life. The vehicle has more instruments than the four rovers preceding it, and it’s also carrying gear that could help pave the way for human exploration of Mars. The ... More>>


ASB: Quarterly Economic Forecast Predicts OCR Hike As Early As August 2022

Predictions of interest rate rises have been brought forward 12 months in ASB’s latest Quarterly Economic Forecast. Chief Economist Nick Tuffley now expects the RBNZ to begin raising the OCR from its current level of 0.25% as early as August ... More>>

Real Estate: House Price Growth Rates In Hawke’s Bay Skyrocket Ahead Of Rest Of New Zealand

Hawke’s Bay is leading the property ‘pack’ proving a post lockdown land of milk and money, continuing to outstrip the rest of the country with the highest annual growth rate in house price values. But experts warn an overheated market is fast ... More>>

ACT: Matariki Almost A Half Billion Dollar Tax On Business

“Official advice to the Government says an extra public holiday at Matariki could cost almost $450 million,” ACT Leader David Seymour can reveal. “This is a perfect example of the Prime Minister doing what’s popular versus what’s responsible. ... More>>

Genesis: Assessing 6,000 GWh Of Renewable Generation Options For Development By 2025

Genesis is assessing 6,000 GWh of renewable generation options for development after starting a closed RFP process with 11 partners. Those invited to participate offer a range of technologies as Genesis continues to execute its Future-gen strategy to ... More>>

OECD: Unemployment Rate Stable At 6.9% In December 2020, 1.7 Percentage Points Higher Than In February 2020

The OECD area unemployment rate was stable at 6.9% in December 2020, remaining 1.7 percentage points above the level observed in February 2020, before the COVID-19 pandemic hit the labour market. [1] In December, the unemployment rate was also stable ... More>>

Stats NZ: Unemployment Drops To 4.9 Percent As Employment Picks Up

The seasonally adjusted unemployment rate dropped to 4.9 percent in the December 2020 quarter, from 5.3 percent in the September 2020 quarter, Stats NZ said today. Last quarter’s unemployment rate of 5.3 percent followed the largest increase observed ... More>>