News Video | Policy | GPs | Hospitals | Medical | Mental Health | Welfare | Search


Urinary Tract Infections And Antibiotic Resistance

Urinary Tract Infections And Antibiotic Resistance In The Community

Novel research results by the Christchurch School of Medicine and Health Sciences, Otago University, shows how difficult it can be for GPs to decide whether or not to prescribe antibiotics for common symptoms of Urinary Tract Infections (UTI) in women. GPs have become wary about over prescribing antibiotics in order to avoid encouraging antibiotic resistance, which is a growing clinical problem world-wide.

This latest research, recently published in the prestigious ‘British Medical Journal’, by Dr Dee Richards and colleagues Professors Les Toop and Steve Chambers provides some evidence to help GPs in the dilemma they face; to prescribe antibiotics for UTI symptoms, or not to prescribe?

The study of women in the Christchurch community, in collaboration with Pegasus Health GPs, is the first of its kind in the country. It looked at 59 women who presented with symptoms but a negative dipstick urine test for infection in the surgery, and in subsequent laboratory analysis. These women were then divided randomly in two groups; one group was given the first line antibiotic trimethoprim, while the other was given a placebo.

“It’s a common dilemma for GPs when a woman has symptoms of a UTI, but the standard urine test is negative for bacterial infection. While wanting to relieve the unpleasant symptoms they don’t want to prescribe drugs unnecessarily. A significant proportion of women with symptoms fall into this group “

Interestingly the results show for the first time, that that even though the initial dipstick test indicated they did not have a UTI, the women who took antibiotics recovered more quickly than those who took a placebo. The median time for symptoms to disappear was three days for those on antibiotics, compared to five for those in the placebo group.

“This information is very helpful to GPs in making a decision about whether to prescribe or not. However these results do indicate that further research is needed for those women who test negative for UTIs, to understand why they actually benefited from antibiotics, even though the front-line dipstick test and the subsequent laboratory test indicated they didn’t have a bacterial infection,” says Dr Richards.

She says the results suggest there may be other causes for the UTI symptoms than those picked up by the standard dipstick urine test.

The second area of recent research looked at levels of antibiotic resistance in the Christchurch community using samples of UTIs collected by 76 Pegasus Health GPs who are part of the Christchurch Sentinel GP Network, and then submitting them for laboratory analysis.

“This study suggests the possibility of increasing resistance compared to previous research. Overall we estimate that women with a positive urine test have trimethoprim resistance of 7.4% compared to 2.7% in 2000. However, a third study with more participants, is now required to confirm whether this is a significant trend to increasing resistance to antibiotics.”

Dr Richards says these results demonstrate the importance of monitoring of antibiotic resistance in the community. The Christchurch Sentinel GP Network is the only one in the country performing this surveillance. It has just completed a third study looking at MRSA.

This research has been funded by Pegasus Health, the Health Research Council and the Canterbury Medical Research Foundation .


© Scoop Media

Culture Headlines | Health Headlines | Education Headlines


Scoop Review Of Books: Salt River Songs by Sam Hunt

Colin Hogg, a longtime comrade of Sam, writes in his Introduction that, ‘There is a lot of death in this collection of new poems by my friend Sam Hunt. It’s easier to count the poems here that don’t deal with the great destroyer than it is to point to the ones that do.’ More>>

Electronica: Restoring The World’s First Recorded Computer Music

University of Canterbury Distinguished Professor Jack Copeland and UC alumni and composer Jason Long have restored the earliest known recording of computer-generated music, created more than 65 years ago using programming techniques devised by Alan Turing. More>>


Scoop Review Of Books: Almost Getting Away With Murder

The Black Widow by Lee-Anne Cartier: Lee-Anne Cartier is the sister of the Christchurch man found to have been murdered by his wife, Helen Milner, after an initial assumption by police that his death, in 2009, was suicide. More>>

Howard Davis: Triple Echo - The Malevich/Reinhardt/Hotere Nexus

Howard Davis: The current juxtaposition of works by Ralph Hotere and Ad Reinhardt at Te Papa perfectly exemplifies Jean Michel Massing's preoccupation with the transmigration of imagery in a remarkable triple echo effect... More>>

Scoop Review Of Books: Nō Tāu Manawa

Vaughan Rapatahana responds to Fale Aitu | Spirit House by Tusiata Avi: "fa’afetai Tusiata, fa’afetai, / you’ve swerved & served us a masterclass corpus / through graft / of tears & fears..." More>>

9 Golds - 21 Medals: NZ Team Celebrates As Rio 2016 Paralympic Games Close

The entire New Zealand Paralympic Team, led by kiwi sprinter and double gold medallist Liam Malone as flag bearer, are on the bus to the Maracanã Stadium in Rio de Janeiro for the Closing Ceremony of the Rio 2016 Paralympic Games. There, they will celebrate the fantastic successes of the past 10 days. More>>


New Zealand Improv Festival: The Festival Of Moments To Return To The Capital

The eighth incarnation of the New Zealand Improv Festival comes to BATS Theatre this 4-8 October , with a stellar line-up of spontaneous theatre and instant comedy performed and directed by top improvisors from around New Zealand and the world. More>>


Get More From Scoop



Search Scoop  
Powered by Vodafone
NZ independent news